abstract：:The rhizome of Acorus tatarinowii is a well-known traditional Chinese medicine. Our extensive investigation on this plant material afforded two new compounds, including a cadinane-type sesquiterpenoid and a pyrazine derivative, along with seven known compounds. The structures of the new compounds, tatarinowin B and ta...

journal_title：Journal of Asian natural products research

authors： Tong XG,Qiu B,Luo GF,Zhang XF,Cheng YX

更新日期：2010-06-01 00:00:00

abstract：:Three new C(19)-diterpenoid alkaloids, umbrosumines A-C (1-3), and 11 known compounds (4-14) were isolated from the roots of Delphinium umbrosum. Their structures were elucidated on the basis of the spectroscopic data interpretation. ...

journal_title：Journal of Asian natural products research

authors： Chen FZ,Chen QH,Wang FP

更新日期：2010-06-01 00:00:00

abstract：:Suberoylanilide hydroxamic acid (1), as well as other histone deacetylase (HDAC) inhibitors, are promising, targeted anticancer agents. Curcumin (2), a possible antitumor agent, exhibits a HDAC inhibiting effect but with a different mechanism, and was proposed to synergize with other drugs, including HDAC inhibitors. ...

journal_title：Journal of Asian natural products research

authors： Zhao JY,Lu N,Yan Z,Wang N

更新日期：2010-05-01 00:00:00

abstract：:A new sterol, stigmast-5-ene-3beta,17alpha-diol (1), together with six known compounds, stigmast-5-ene-3beta-yl formate (2), stigmast-5-ene-3beta,7alpha-diol (3), stigmast-5-ene-7alpha-methoxy-3beta-ol (4), stigmast-5-ene-3-one (5), 3beta-sitostanol (6), and 3beta-sitosterol (7), was isolated from the fruits of Syzygi...

journal_title：Journal of Asian natural products research

authors： Chumkaew P,Kato S,Chantrapromma K

更新日期：2010-05-01 00:00:00

abstract：:A profiling analysis of the total isoflavone extract of the root of Pueraria lobata (Wild.) Ohwi was performed using HPLC coupled with ESI-ion trap mass spectrometry. A total of seven isoflavones were identified according to their retention times, UV, MS data, and comparing with the literature data. Among them, two pr...

journal_title：Journal of Asian natural products research

authors： Zhang HJ,Yang XP,Wang KW

更新日期：2010-04-01 00:00:00

abstract：:Dehydrozingerone analogs and related compounds were screened as potential antitumor promoters by using the in vitro short-term 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced Epstein-Barr virus early antigen activation assay. Among the 40 synthesized compounds, the prenylated analogs 16 and 34-36 showed the most si...

journal_title：Journal of Asian natural products research

authors： Tatsuzaki J,Nakagawa-Goto K,Tokuda H,Lee KH

更新日期：2010-03-01 00:00:00

abstract：:A palmatine derivative, named 11-hydroxypalmatine (4), has been isolated from the tubers of Stephania glabra, together with three known alkaloids, palmatine (1), dehydrocorydalmine (2), and stepharanine (3). The structures of the compounds were elucidated by means of spectroscopic analysis including 2D NMR experiments...

journal_title：Journal of Asian natural products research

authors： Semwal DK,Rawat U,Semwal R,Singh R,Singh GJ

更新日期：2010-02-01 00:00:00

abstract：:Phytochemical investigation of the roots of Arisaema jacquemontii led to the isolation of two new triterpenoids, which were characterized by NMR, IR, and MS spectra as 30-nor-lanost-5-ene-3beta-ol (1) and 30-norlanost-5-ene-3-one (2). ...

journal_title：Journal of Asian natural products research

authors： Jeelani S,Khuroo MA,Razadan TK

更新日期：2010-02-01 00:00:00

abstract：:Two new steroidal saponins were isolated from the fruits of Tribulus terrestris L. Their structures were elucidated by spectroscopic and chemical analysis as (23S,24R,25R)-5alpha-spirostane-3beta,23,24-triol-3-O-{alpha-L-rhamnopyranosyl-(1 --> 2)-[beta-D-glucopyranosyl-(1 --> 4)]-beta-D-galactopyranoside} (1) and (23S...

journal_title：Journal of Asian natural products research

authors： Liu T,Lu X,Wu B,Chen G,Hua HM,Pei YH

更新日期：2010-01-01 00:00:00

abstract：:A new triterpene glycoside mutongsaponin F (1), together with five known saponins and two known lipids, was isolated from the 70% ethanol extract of the stems of Akebia trifoliata (Thunb.) Koidz. var. australis (Diels) Rehd. Their structures were elucidated on the basis of the spectroscopic analysis and physicochemica...

journal_title：Journal of Asian natural products research

authors： Gao HM,Wang ZM,Wang WH

更新日期：2009-12-01 00:00:00

abstract：:A new sesquiterpene cacaroborin (1) was isolated from the roots of Cacalia roborowskii, together with three known ones, cinalbicol (2), isopetasin (3), and 3alpha-angeloyloxylactone (4). The structure of compound 1 was elucidated as 1beta,10alpha-dihydroxy-8alpha-methoxyeremophil-7(11)-en-8beta,12-olide on the basis o...

journal_title：Journal of Asian natural products research

authors： Zhang ZX,Fei DQ

更新日期：2009-11-01 00:00:00

abstract：:A novel series of acylide derivatives have been synthesized which exhibit in vitro potency against key respiratory pathogens. Modification of position 3 was accomplished by replacing different 3-O-substituted acyl groups in the macrolide core via a facile procedure. Compounds 7a-7i were eventually yielded by the conju...

journal_title：Journal of Asian natural products research

authors： Xu P,Liu L,He W,Li Y,Liu J,Lei PS

更新日期：2009-10-01 00:00:00

abstract：:Chrysoeriol (1) was isolated as the main constituent from the methanol extract of the dried leaves of Eurya ciliata Merr. To investigate the bioactivities of 1 on bone metabolism, its effects on the function of osteoblastic MC3T3-E1 cells were studied. Compound 1 significantly increased the growth of MC3T3-E1 cells an...

journal_title：Journal of Asian natural products research

authors： Tai BH,Cuong NM,Huong TT,Choi EM,Kim JA,Kim YH

更新日期：2009-09-01 00:00:00

abstract：:A new natural coumarin, angepubebisin (1), and a new furan, angepubefurin (2), together with the five known compounds, umbelliferone, angelol B (3), ulopterol (4), peucedanol (5), and scopoletin, were isolated from the roots of Angelica pubescens Maxim. f. biserrata Shan et Yuan. The structures of angepubebisin (1) an...

journal_title：Journal of Asian natural products research

authors： Yang XW,Zhang CY,Zhang BG,Lu Y,Luan JW,Zheng QT

更新日期：2009-08-01 00:00:00

abstract：:A new amide alkaloid, N-(3',4',5'-trimethoxy-cis-cinnamoyl)pyrrolidine (1), named sarmentomicine was isolated from the ethanol extract of the leaves of Malayan Piper sarmentosum, together with two known phenylpropanoids. Their structures were elucidated on the basis of spectroscopic analysis. ...

journal_title：Journal of Asian natural products research

authors： Sim KM,Mak CN,Ho LP

更新日期：2009-08-01 00:00:00

abstract：:Two new phenolic glycosides were isolated from the seeds of Cucurbita moschata. Their structures were elucidated as (2-hydroxy)phenylcarbinyl 5-O-benzoyl-beta-D-apiofuranosyl(1-->2)-beta-D-glucopyranoside (1) and 4-beta-D-(glucopyranosyl hydroxymethyl)phenyl 5-O-benzoyl-beta-D-apiofuranosyl(1-->2)-beta-D-glucopyranosi...

journal_title：Journal of Asian natural products research

authors： Li FS,Dou DQ,Xu L,Chi XF,Kang TG,Kuang HX

更新日期：2009-07-01 00:00:00

abstract：:Four new minor taxanes (1-4) have been isolated from Ts-19 cell cultures of Taxus chinensis together with five known taxanes (5-9) by silica gel chromatography combined with semi-preparative HPLC chromatography. On the basis of the analyses of the chemical and spectroscopic (IR, MS, 1D, and 2D NMR) data, the structure...

journal_title：Journal of Asian natural products research

authors： Xie D,Jia HT,Zhang Y,Zou JH,Yin DL,Chen XG,Yan YN,Dai JG

更新日期：2009-06-01 00:00:00

abstract：:Three new triterpene saponins, ilekudinosides T-V (1-3), along with six known saponins were isolated from the 70% ethanolic extract of the leaves of Ilex kudingcha. The new saponins were characterized as 3-O-beta-d-glucopyranosyl-(1 --> 3)-[alpha-l-rhamnopyranosyl-(1 --> 2)]-alpha-l-arabinopyranosyl-3beta,19alpha-dihy...

journal_title：Journal of Asian natural products research

authors： Tang L,Jiang Y,Tian XM,Zhou SX,Tu PF

更新日期：2009-06-01 00:00:00

abstract：:Ophiopogon japonicus polysaccharide (FOJ-5) from Radix ophiopogonis has shown anti-myocardial ischemic action in vitro and in vivo in our previous studies. In order to clarify the influence of chemical modifications on the action, a series of sulfated FOJ-5 (FOJ-5-S) with different substitution degrees were prepared a...

journal_title：Journal of Asian natural products research

authors： Zheng Q,Feng Y,Xu DS,Lin X,Chen YZ

更新日期：2009-01-01 00:00:00

abstract：:Our goals were to examine the dual-directional regulation effects of resveratrol (1) in vitro by using MCF-7 cells (estradiol receptor-positive cells), study its mechanism of action, and give a systematical analysis of the regulatory networks of each related factor. An MTT test and growth curve showed that the prolife...

journal_title：Journal of Asian natural products research

authors： Wang YZ,Cao B,Li SX,Zang ZH,Zhang JZ,Chen H

更新日期：2009-01-01 00:00:00

abstract：:In the title study, the synthesis of the vital intermediate C-nor-aconanone (3) from 4 was completed through 11 steps, mainly including semipinacol rearrangement, formation of the imines by the treatment of 10 or 20 with NBS, the cleavage of N-C19 bonds in 11 or 21 by treatment with m-CPBA and subsequently with LTA, a...

journal_title：Journal of Asian natural products research

authors： Shen XL,Chen QH,Wang FP

更新日期：2009-01-01 00:00:00

abstract：:A new naphthalene derivative, 1-methyl-2,3-methylenedioxy-6-naphthalenecarboxylic acid methyl ester (1), and a new alkaloid, ( +/- )-1-phenyl-2-imido-1-propanol (2), together with the four known compounds, ephedrine, pseudoephedrine, N-methylephedrine, and 6-methoxykynurenic acid, have been isolated from the stems of ...

journal_title：Journal of Asian natural products research

authors： Zhao W,Deng AJ,Du GH,Zhang JL,Li ZH,Qin HL

更新日期：2009-01-01 00:00:00

abstract：:A new triterpenoid saponin named clematichinenoside AR(2), along with the six known compounds, was isolated and characterized from Clematis chinensis Osbeck (Ranunculaceae), a commonly used traditional Chinese medicine with anti-inflammatory and anti-rheumatoid activities. The structure of the new saponin was elucidat...

journal_title：Journal of Asian natural products research

authors： Liu LF,Ma XL,Wang YX,Li FW,Li YM,Wan ZQ,Tang QL

更新日期：2009-01-01 00:00:00

abstract：:Three new xanthones, 1,3-dihydroxy-2,5,6,7-tetramethoxyxanthone (1), 3-hydroxy-1,2,5,6,7-pentamethoxyxanthone (2), and 3,8-dihydroxy-1,2,6-trimethoxyxanthone (3), together with two known compounds were isolated from the roots of Polygala japonica Houtt. Their structures were determined on the basis of spectroscopic da...

journal_title：Journal of Asian natural products research

authors： Xue QC,Li CJ,Zuo L,Yang JZ,Zhang DM

更新日期：2009-01-01 00:00:00

abstract：:Verticilliside (1), a new flavone C-glucoside, has been isolated from the ethyl acetate soluble fraction of Enicostemma verticillatum and its structure is assigned on the basis of the spectroscopic data. 5,7,4'-Trihydroxyflavone 8-C-beta-D-glucopyranoside (2) and isoorientin 3'-O-methyl ether (3) have also been isolat...

journal_title：Journal of Asian natural products research

authors： Jahan E,Perveen S,Malik A

更新日期：2009-01-01 00:00:00

abstract：:A novel 2,3-secoaromadendrane-type sesquiterpenoid metabolite, psilosamuiensin A (1), was isolated from the broth of Psilocybe samuiensis. The structure of psilosamuiensin A was established by spectroscopic data and its configurations were confirmed by single crystal X-ray crystallographic analysis. This is the first ...

journal_title：Journal of Asian natural products research

authors： Pornpakakul S,Suwancharoen S,Petsom A,Roengsumran S,Muangsin N,Chaichit N,Piapukiew J,Sihanonth P,Allen JW

更新日期：2009-01-01 00:00:00

abstract：:Bioassay-guided fractionation of the ethanolic extract of Senecio scandens led to the isolation of four new compounds 4, 5, 7, and 8, along with four known jacaranone analogs (1, 2, 3, 6). Their structures were elucidated on the basis of spectral and chemical evidence. Compound 7 was obtained as a tautomeric mixture o...

journal_title：Journal of Asian natural products research

authors： Tian XY,Wang YH,Yang QY,Yu SS,Fang WS

更新日期：2009-01-01 00:00:00

abstract：:An investigation of CH(2)Cl(2) and EtOH extracts of Trifolium resupinatum L. var. microcephalum Zoh. has led to the isolation of two new compounds characterized as 4,15-dimethyl-2-(1,2-dihydroxyethyl)-hexadecene (1) and 1-undecene-1-O-beta-2',3',4',6'-tetraacetyl glucopyranoside (2a). Their structures were established...

journal_title：Journal of Asian natural products research

authors： Sabudak T,Isik E,Oksuz S

更新日期：2008-11-01 00:00:00

abstract：:Two new compounds, 3-O-(13-hydroxy-9Z,11E,15E-octadecatrienoyl) cycloeucalenol (1) and 24'-hydroxy-tetracosyl ferulate (2), together with one known compound, tetracosyl ferulate (3), were isolated from the dried stems of Gnetum pendulum. The two new compounds were structurally elucidated by spectroscopic and chemical ...

journal_title：Journal of Asian natural products research

authors： Xiang WS,Wang JD,Wang XJ,Zhang J

更新日期：2008-11-01 00:00:00

abstract：:Two new flavonoid alkaloids, 8-(2''-pyrrolidinone-5''-yl)-quercetin (1) and 8-(2''-pyrrolidinone-5''-yl)-isorhamnetin (2), were isolated from the herb of Senecio argunensis. Their structures were elucidated by spectral analysis. ...

journal_title：Journal of Asian natural products research

authors： Li N,Shao L,Zhang CF,Zhang M

更新日期：2008-11-01 00:00:00

abstract：:A novel alkaloid, hupcrispatine (1), has been isolated from the unique Chinese species Huperzia crispate Ching. The structure of hupcrispatine has been elucidated as 9-amino-6-methyl-3-quinolone on the basis of spectral evidence. ...

journal_title：Journal of Asian natural products research

authors： Pei G,He GX,Du FL,Jiang DS

更新日期：2008-09-01 00:00:00

abstract：:Four nitrogen-containing derivatives of ginkgolide B were synthesized to improve the physical-chemical properties and bioavailability of ginkgolide B. The reaction was accomplished with the nitrogen atom as neighboring group participating in the replacement reaction. All of the four compounds were proved to have excel...

journal_title：Journal of Asian natural products research

authors： Guo CJ,Ren Y,Qin YL,Zhang Q

更新日期：2008-09-01 00:00:00

abstract：:Four new oleanane-type triterpenoid saponins, cyclamiretin A 3beta-O-alpha-L-rhamnopyranosyl-(1 --> 3)-[beta-D-xylopyranosyl-(1 --> 2)]-beta-D-glucopyranosyl-(1 --> 4)-[beta-D-glucopyranosyl-(1 --> 2)]-alpha-L-arabinopyranoside (1), cyclamiretin A 3beta-O-alpha-L-rhamnopyranosyl-(1 --> 3)-[beta-D-glucopyranosyl-(1 -->...

journal_title：Journal of Asian natural products research

authors： Wen P,Zhang XM,Yang Z,Wang NL,Yao XS

更新日期：2008-09-01 00:00:00

abstract：:Two new lanostanoid triterpenes, 23S-hydroxy-3,7,11,15-tetraoxo-lanost-8,24E-diene-26-oic acid (1), and 12beta-acetoxy-3beta-hydroxy-7,11,15,23-tetraoxo-lanost-8,20E-diene-26-oic acid (16), together with 17 known compounds, were isolated from the fruit bodies of Ganoderma lucidum. Their structures were established by ...

journal_title：Journal of Asian natural products research

authors： Guan SH,Xia JM,Yang M,Wang XM,Liu X,Guo DA

更新日期：2008-07-01 00:00:00

abstract：:Two new acylgluconic acids, trans-feruloylgluconic acid (1) and trans-caffeoylgluconic acid (2), together with three known compounds, myo-inositol (3), phthalic acid dibutyl ester (4), and wuzhuyuamide-I (5), were isolated from the water soluble part of the dried nearly ripe fruits of Evodia rutaecarpa (Juss.) Benth. ...

journal_title：Journal of Asian natural products research

authors： Zhao MY,Yang XW

更新日期：2008-07-01 00:00:00

abstract：:A new hTopo I isomerase inhibitor, (+)-3,3',7,7',8,8'-hexahydroxy-5,5'-dimethylbianthraquinone (2240A), was isolated from the mangrove endophytic fungus no. 2240 collected from an estuarine mangrove at the South China Sea coast. Its structure was elucidated by spectral analyses including two-dimensional NMR, HR-EI-MS,...

journal_title：Journal of Asian natural products research

authors： Tan N,Cai XL,Wang SY,Pan JH,Tao YW,She ZG,Zhou SN,Lin YC,Vrijmoed LL

更新日期：2008-07-01 00:00:00

abstract：:Two new xanthone O-glycosides, polyhongkongenosides A (1) and B (2), together with four known xanthone glycosides, were isolated from the herbs of Polygala hongkongensis Hemsl. Their structures were elucidated on the basis of UV, IR, NMR, and MS spectral data. The antioxidant in vitro activities of 1-6 were determined...

journal_title：Journal of Asian natural products research

authors： Wu JF,Chen SB,Gao JC,Song HL,Wu LJ,Chen SL,Tu PF

更新日期：2008-07-01 00:00:00

abstract：:A new benzofuran-type lignan, vitrifol A (1), was isolated from the fruits of Vitex trifolia, along with three known compounds 2-4. Their structures were elucidated mainly on the basis of 1D, 2D NMR and MS spectral data. Compound 1 was first isolated as a dimer of dihydrobenzofuran-type lignan. ...

journal_title：Journal of Asian natural products research

authors： Gu Q,Zhang XM,Zhou J,Qiu SX,Chen JJ

更新日期：2008-05-01 00:00:00

abstract：:Carpesides A (1) and B (2), two new 8-O-4'-neolignan glucosides, and eupatriol 9-O-beta-d-apiofuranosyl-(1 --> 6)-beta-d-glucopyranoside (3), one new monoterpenoid diglycoside, together with 10 known glycosidic compounds, were isolated from the aerial part of Carpesium cernuum L. The structures of the new glycosides a...

journal_title：Journal of Asian natural products research

authors： Ma JP,Tan CH,Zhu DY

更新日期：2008-05-01 00:00:00

abstract：:Two new furostanol saponins, tribufurosides B (1) and C (2), were isolated from the fruits of Tribulus terrestris L. With the help of chemical and spectral analyses (IR, MS, 1D NMR and 2D NMR), the structures of two new furostanol saponins were established as 26-O-beta-d-glucopyranosyl-(25S)-5alpha-furost-20(22)-en-2a...

journal_title：Journal of Asian natural products research

authors： Xu TH,Xu YJ,Xie SX,Zhao HF,Han D,Li Y,Niu JZ,Xu DM

更新日期：2008-05-01 00:00:00